GARCINOL ENHANCES TRAIL-INDUCED APOPTOTIC CELL DEATH THROUGH UP-REGULATION OF DR5 AND DOWN-REGULATION OF C-FLIP EXPRESSION

Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression

Garcinol is a polyisoprenylated benzophenone derived from the Garcinia indica fruit that possess potential therapeutic effects such as inhibition of inflammation and tumor expansion.Here, we investigated whether garcinol induces TRAIL sensitization in renal carcinoma cells.Single treatment with garcinol or TRAIL did not effect on apoptosis.However,

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Characterization of testis-specific serine/threonine kinase 1-like (TSSK1-like) gene and expression patterns in diploid and triploid Pacific abalone (Haliotis discus hannai; Gastropoda; Mollusca) males.

Testis-specific serine/threonine kinase 1-like (TSSK1-like), which plays important roles in late-phase spermatogenesis and male fertility, was characterized in Pacific abalone Haliotis discus hannai, an important commercial marine gastropod.Further, its expression patterns were assessed in diploid and induced triploid males showing differential deg

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